11 results
hematology leukemia differential lymphocytic mds myelodysplastic aplastic causes common cvid essential et hemeonc hypogammaglobulinemia immunodeficiency immunology myelodysplasia platelets syndromes tafro
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Algorithm Spurious ... effect following treatment ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... #Algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
basophilia, and thrombocytosis ... - infiltrates (anemia ... , thrombocytopenia ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... or thrombocytopenia ... #Leukemia #oncology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Neutropenia, anemia ... , thrombocytopenia ... microglobulin Treatment ... #workup #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... Marrow Failure • Chronic ... IDUS) • Immune Thrombocytopenia ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... infections/fevers • Thrombocytopenia ... Treatment: ... #oncology #hematology ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... specifically immune thrombocytopenia ... autoimmune hemolytic anemia ... #diagnosis #management
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
(ET) ET is a chronic ... PV, MDS, CML) Treatment ... • Treatment algorithms ... Hydroxyurea + anticoagulation ... #diagnosis #management
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