13 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... HUS (aHUS) ... Microangiopathy #TMA #hematology ... #differential #
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... o CML - bcr-able ... o Other bcr-able ... #hematology #Markers ... #Differential #
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP VS HUS ... Often hard to differentiate ... HemolyticUremicSyndrome #HUS ... Comparison #Diagnosis #Table ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... disease - DIC/TTP/HUS ... : • DIC, TTP/HUS ... #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... menstrual - Recent procedures ... or if a primary hematologic ... #Differential # ... Causes #Workup #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... DIC, TTP, HELLP, HUS ... Consider RBC membrane disorder ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
uremic syndrome (HUS ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
whereas edoxaban has ... Dabigatran has moderate ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Causes: - Allergic disorders ... - Immunologic disorders ... HES - HES Undetermined ... eosinophilia #diagnosis #hematology ... #differential #
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... Defects #comparison #table ... #differential # ... diagnosis #hematology