15 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... /DM), Systemic sclerosis ... , Interstitial Pulmonary ... ANA #patterns #rheumatology ... #diagnosis #differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... fraction < 20% Differential ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... patients with clinically ... stimulation Clinical ... #diagnosis #management ... #neurology #treatment
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Diagnosis Neurologic-Centered ... : • Systemic capillary ... Ig deposition disease ... #Diagnosis #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
exudates) - SLE • Scleritis ... Pulmonary ... syndrome - SLE Neurologic ... #joint #pain #differential ... #diagnosis #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Clarkson/Systemic capillary ... et diutinum Neurologic ... DADS-M • POEMS (Sclerotic ... #Monoclonal #Differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... , particularly scleritis ... affects the skin, neurologic ... cognitive impairment, neurologic ... #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... skin injury) • Neurologic ... ) Differential Diagnosis ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... course of the disease ... conditions listed in differential ... #neurology #diagnosis ... #management
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
- Capillary leak ... Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... syndrome #diagnosis #management ... timeline #treatment #rheumatology