31 results
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... anticoagulants (DOACs ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... metabolization of DOACs ... Chemotherapy #Oncology #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... #Cancer #Algorithm ... Anticoagulation #Management #Hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... #Reversal #NOAC ... anticoagulant #hematology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... Indications #Management #Cirrhosis ... #treatment #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Infiltrative • Cirrhosis ... • Pancreatic cancer ... Others #LFTs #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
CIRRHOSIS - ... Progression to cirrhosis ... without PSC • CANCER ... hepato-biliary cancers ... management #summary #Hepatology
Portal Vein Thrombosis (PVT) Treatment Algorithm
 - If concern for ischemic: anti-coag+multidisciplinary care
 - W/o cirrhosis+recent
Thrombosis (PVT) Treatment ... Algorithm - If concern ... multidisciplinary care - W/o cirrhosis ... anti-thrombotic tx - Cirrhosis ... management #Algorithm #hepatology