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hematology syndrome hemophagocytic lymphohistiocytosis summary activation adultonset behcet cancer capillary cell clarksons classification criticalcare differential fungal gastroenterology hemeonc hemochromatosis hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Differential Diaqnoses ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
- Differential Diagnosis ... , Severe Valve Disease ... • Obstructive: Pulmonary ... #criticalcare #algorithm ... #treatment #management
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... • Treatment algorithms ... von Willebrand disease ... #Management #Summary ... #treatment #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... search for and treatment ... ▪ Autoimmune diseases ... Treatment Approach ... #Management #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymph node biopsy (diagnostic ... number of sites of disease ... Hodgkin Lymphoma Treatment ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Algorithm regarding ... the diagnosis and ... treatment of Hereditary ... causes of liver disease ... #diagnosis #management
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