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diagnosis signs hepatology complications management phosphatase algorithm ankylosingspondylitis anorexianervosa apml biliary cholangitis cirrhosis dermatomyositis diabetes diabeticketoacidosis differential differentiation dm elevation
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... Bone growth) Alkaline ... Most common symptoms ... Pregnancy - Renal ... disease - Bone symptoms
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Low Alkaline Phosphatase ... collection with EDTA Pathophysiology ... mineralization Symptoms ... neuropathy • Renal ... : - Renal failure
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... patient has good renal ... resolves due to ATP ... Signs/Symptoms/Complications ... #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs / Symptoms ... spread • Sub-retinal ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
them to adhere to renal ... saprophyticus, Serratia ... UrinaryTractInfection #UUTI #Pathophysiology ... #Signs #Symptoms
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... PBC Signs and Symptoms ... PBC Labs: • Alkaline ... Nucleotidase • ALT ... obstruction • ALP
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
aminotransferase (AST), and alanine ... aminotransferase (ALT ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... Anaphylaxis, Acute Renal
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... • Symptoms: Fever ... pulses • The Renal ... Measure lactate in all
Rickets and Osteomalacia: Pathogenesis and Clinical Findings • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
enzymes (like ALP ... Phosphate: renal ... #Osteomalacia #pathophysiology ... diagnosis #signs #symptoms
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