7210 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... heliotrope rash, Shaw ... triad of ILD, myositis ... #Autoimmune #Myositis
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
periorbital heliotrope, shawl ... Necrotizing Autoimmune Myositis ... Inclusion Body Myositis
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... MithuRheum #Myositis ... Antibodies #MSAs #clinical
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
Myositis and Myopathies ... Inclusion body myositis
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... Inclusion Body Myositis ... , +Anti-dsDNA, Myositis ... BostonChiefs #Myositis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Inclusion body myositis ... Pyomyositis, Lyme myositis ... Malignancy-associated myositis ... anti-RNP - (Myositis ... inclusion body myositis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... • Transverse myelitis ... positive NMO only): Myositis
Magic Mouthwash for Oral Mucositis

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2715162

Visual Abstract by Chanjun S Park @s_chanjun

#Magic #Mouthwash #Mucositis #EBM #VisualAbstract #Management
Mouthwash for Oral Mucositis ... Magic #Mouthwash #Mucositis
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Inclusion Body Myositis
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
heliotrope rash, 2) shawl ... Gottrons #Papules #Clinical