15 results
differential lfts transaminitis management acute causes elevation function gastroenterology hepatitis interpretation pathophysiology tests abnormal aclf aflp alkaline arterial chemistry chronic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Algorithm DILI ... #Injury #Diagnosis ... #Algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... #Liver #Injury # ... gastroenterology #algorithm ... gastroenterology #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili ... Hepatocellular injury ... 2: Cholestatic injury ... Transaminitis #diagnosis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... #algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... #hepatology #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
• Liver injury ... Unconjugated Bili ... > 90% of Total Bili ... #chemistry #diagnosis ... #differential #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... or AST > ALP): ... 15X ULN - Drugs ... #diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... 10x ULN), ↑Tbili/Dbili ... ) Differential Diagnosis ... Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Diagnosis Framework ... : Liver Injury ... valproate, azoles), Drugs ... #Diagnosis #hepatology ... #algorithm #Transaminitis
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