14 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Differential Diagnosis Algorithm ... Myelofibrosis Stem cell ... • Toxins • Aplastic ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... ITP • SLE • CLL ... #Causes #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... infections from neutropenia ... Consider stem cell ... antibiotics if neutropenic ... management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... aplasia • ITP ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infiltrates (anemia, thrombocytopenia ... or functional neutropenia ... Phosphorus CLL ... transformation of the CLL ... #Leukemia #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Difficulty breathing • Neutropenia ... infections/fevers • Thrombocytopenia ... Anemia #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
ferritin, Anemia, Thrombocytopenia ... , Neutropenia, ↑ ... d-dimer, ↓ NK cell ... (affecting 2 2 cell ... Lymphohistiocytosis #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Symptoms of anemia or thrombocytopenia ... PRCA, autoimmune neutropenia ... with anemia or thrombocytopenia ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell ... Schistocytes, thrombocytopenia ... Differential #Diagnosis #Algorithm ... #workup #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... Follicularis • Aplasia ... Congenital hair shaft ... HairLoss #Alopecia #dermatology ... Differential #Diagnosis #Algorithm