16 results
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
adult - Algorithm ... #neutropenic #neutropenia ... #Algorithm #workup ... #diagnosis #hematology ... #biopsy #indications
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Differential Diagnosis Algorithm ... Myelofibrosis Stem cell ... #Pancytopenia #Neutropenia ... #Causes #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
infections from neutropenia ... hypocellular bone marrow biopsy ... Consider stem cell ... antibiotics if neutropenic ... management #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
ferritin, Anemia, Thrombocytopenia ... , Neutropenia, ↑ ... d-dimer, ↓ NK cell ... Hemophagocytosis on biopsy ... Lymphohistiocytosis #diagnosis #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... ITP • SLE • CLL ... Heart Valve) #Thrombocytopenia ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infiltrates (anemia, thrombocytopenia ... or functional neutropenia ... Phosphorus CLL ... transformation of the CLL ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... CLL Epidemiology ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... workup #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... not required in all ... or if a primary hematologic ... BM aspiration/biopsy ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... PRCA, autoimmune neutropenia ... with anemia or thrombocytopenia ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... - Irreversible-biopsy ... - Irreversible-biopsy ... Congenital hair shaft ... Differential #Diagnosis #Algorithm