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hepatology diagnosis liver differential injury causes chronic hepatitisb lfts transaminitis treatment aclf ascites chemistry dili druginduced failure gastroenterology hepbv indications
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... Algorithm • ... viremia or have cirrhosis ... #HBV #Algorithm ... #Treatment #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... or fibrosis • Cirrhosis ... > 3 mg/dL) or acute ... #Indications #management ... #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 20x normal - Acute ... normal - Infection (EBV ... /CMV), Alcoholic ... cirrhosis, Portal ... Liver #Injury #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... : Alcohol, Medication ... , Acute biliary ... Medication, Pregnancy, Alcoholic ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... dechallenge • Acute ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... Failure Infections Alcohol-Associated ... Hepatitis (AAH) ... #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... , HBV, HCV, HEV, ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... diseases including HBV ... #Hepatitis #Management ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... ALT Ratios: • Alcoholic ... : < 1 • Cirrhosis ... #differential #Hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
disease - Cirrhosis ... - Alcoholic ... hepatitis ... fibrosis - Acute ... #differential #hepatology
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