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diagnosis rheumatology differential dermatology signs joint classification erythematosus pain systemic arthritis arthropathies arthropathy behcet causes complications conditions cryoglobulinemia cryoglobulins cutaneous
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... infection Malar rash ... gangrenosum • IBD • RA ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... , RA related vasculitis ... nodules, Deep ulcers ... Disease • Cogan syndrome ... #skin #dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... Demyelinating syndromes ... erythematosus #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... > Mouth, Nasal Ulcers ... Livedo Reticularis, Vasculitis ... diagnosis #signs #symptoms
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
, Vasculitis (e.g ... Scrotal or vulvar ulcers ... ENT • Oral ulcers ... Scleroderma Thickened skin ... differential #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Rheumatoid Arthritis (RA ... Erythematosus (SLE ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin ... : • Symptoms limited
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... genital aphthous ulcers ... such as systemic lupus ... Presentation - Systemic Symptoms ... , and SLE) • Urinalysis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... ulcers - Glomerulonephritis ... or RA - 5 to ... reticularis & skin ... (e.g. systemic lupus
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... cryoglobulins • Skin ... #Causes #dermatology
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