43 results
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Adrenal Insufficiency ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... : • High baseline ... #Algorithm #endocrinology
Adrenal Insufficiency Diagnosis Algorithm
Clinical features: 
 - Weight loss, anorexia, Weakness, fatigue, GI distress
 - Hypotension,
Adrenal Insufficiency ... Diagnosis Algorithm ... Hyperpigmented skin (due to high ... Hyponatremia, hyperkalemia ... Stimulation #StimTest #Endocrinology
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
The Diagnostic Approach ... to Hyperkalemia ... inhibitors Other causes ... transplant - SLE High ... insufficiency
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Genetic disorders (e.g ... thyrotoxicosis, adrenal ... insufficiency ... #Diagnosis #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Differential Diagnosis ... Immobilization • Adrenal ... Insufficiency ... #Differential #Diagnosis ... #Algorithm #Endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
of Adrenal Insufficiency ... Serum DHEAS Diagnosis ... Administer 250 mcg ... addisons #disease #endocrinology ... #diagnosis #signs
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Adrenal Insufficiency ... ketoconazole, etomidate) Symptoms ... Hyperkalemia is ... Adrenal Insufficiency ... #Management #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH

Early am cortisol < 3
Adrenal Insufficiency ... unclear (often the case ... Stim test is 250 mcg ... Measure ACTH: - High ... Stimulation #Test #Endocrinology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... insufficiency/Failure ... #causes #potassium
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... Pseudohyperparathyroidism, Renal ... #Causes #differential ... #diagnosis #calcium ... #high #endocrinology