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management differential hepatology syndrome alp bandemia bulimianervosa cbc cerebritis cns complications druginduced erythematosus hepatorenal hrs hyophosphatasia leukostasis low lupus lysis
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... Benyzlpenicillin, blood ... #differential #diagnosis ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
fractures of feet, thigh ... deficiency • blood ... collection with EDTA Pathophysiology ... Hyperlipidemia - Hypercalcemia ... Hyophosphatasia #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Left Shift: • ... with moderate and high ... neutrophil #WBC #CBC #hematology ... #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... thrombosis and/or blood-brain ... permeability Diagnosis ... Lumbar Puncture, EEG ... Induction Rx: high-dose
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... High mortality. ... Hypocalcemia, Hyperkalemia ... #Transfusions #diagnosis ... #management #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... casts, protein, or blood ... Classification: ... liver insult (e.g ... Prognosis: • High
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
Binging on foods high ... acids elevated blood ... ) • Overall: hypokalemia ... Complications #pathophysiology ... #diagnosis #signs
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