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diagnosis management differential algorithm anemia causes erythematosus lupus sle systemic workup alkaline alp cbc cerebritis cns disorders electrophoresis hepatology hodgkins
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease (e.g ... Chronic Infection) High ... #MCV #Classification ... Algorithm #Causes #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Left Shift: • ... with moderate and high ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... of substrate (e.g ... Diagnosis #Workup #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... Induction Rx: high-dose ... CNS #neurology #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
plateletcount), peripheral blood ... function test, ANA (e.g ... psychiatric changes), high ... MCV anemia (vegan ... Causes #Workup #hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• New-onset anemia ... suspected • Hypercalcemia ... possible malignancy (e.g ... on peripheral blood ... Electrophoresis #SPEP #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... Workup: • Full Blood ... - WBC may be high ... marrow biopsy - if blood ... #hematology #oncology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
fractures of feet, thigh ... • Pernicious anemia ... deficiency • blood ... collection with EDTA Pathophysiology ... Hyperlipidemia - Hypercalcemia
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... High mortality. ... Hypocalcemia, Hyperkalemia ... diagnosis #management #hematology
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