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diagnosis management differential product reactions treatment bandemia cbc cerebritis cns druginduced erythematosus leukostasis lupus lysis medications neurology neutrophil pharmacology sle
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... Benyzlpenicillin, blood ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Hyperkalemia Management Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... Blood drawn from ... site/line where potassium ... minutes-hour) -Shift ... #high
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... Induction Rx: high-dose ... CNS #neurology #rheumatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Left Shift: • ... with moderate and high ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... High mortality. ... Hypocalcemia, Hyperkalemia ... potassium from ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... High mortality. ... Hypocalcemia, Hyperkalemia ... potassium from ... diagnosis #management #hematology
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