23 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
shift of K (Succinylcholine ... #differential #diagnosis ... #pathophysiology ... #pharmacology #potassium ... #medications #druginduced
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift ... Thyrotoxicosis Medications ... vomiting) • Low K ... nephrology #low #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... insufficiency/Failure • SLE ... Medications 2.
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential Diagnosis ... Transcellular Shift ... Algorithm #causes #potassium ... #low #pathophysiology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... phlebotomy High ... Intracellular Shift ... insufficiency/Failure • SLE ... Medications 2.
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... TTKG should be high ... #Differential #Diagnosis ... Algorithm #causes #potassium ... #high #pathophysiology
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... transcellular shifts ... renal function, medication ... is rarely the sole ... dysfunction is common #Diagnosis
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
depletion • Consider K+ ... and ECG changes ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... syndrome #hypokalemia ... #urine #potassium ... differential #algorithm #diagnosis
Causes of Hyperkalemia - Differential Diagnosis Framework
 • Cellular Shift:
   - Exercise
Framework • Cellular Shift ... hyperosmolality - Medications ... to Aldosterone: K ... #Causes #potassium ... #high