17 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... differential #diagnosis #pathophysiology ... #pharmacology #
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Curve Left Shift ... Temperature Right Shift ... ↑ 2,3-BPG • High ... Dissociation #Curve #pathophysiology ... #pulmonary #respiratory
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... potassium and ECG ... blocks, QRS axis shift ... , asystole #hyperkalemia ... #potassium #high
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Blood Pressure, Pulmonary ... Dobutamine 2-20 mcg ... - Dopamine, high ... 10-20 mcg/kg/min ... Properties #Table #Pharmacology
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
stagnant hypoxia (e.g ... maybe sepsis) - High ... PaO2, High SvO2 ... Hypoxemia #summary #pulmonary ... diagnosis #causes #pathophysiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... - Hyperkalemia ( ... high potassium levels ... #Pathophysiology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Noncardiogenic Pulmonary ... Framework NCPE Pathophysiology ... Noncardiogenic pulmonary ... level <100 pg/ml EKG ... edema • High
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Liver Failure • Hypercalcemia ... Chronic Obstructive Pulmonary ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... unless worrisome EKG
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Diagnosis Framework High ... • High-altitude ... : The shift of fluid ... Edema: • Pathophysiology ... • Pathophysiology