37 results
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk

#MultipleMyeloma
CRAB #SLIMCRAB #Oncology ... #HemeOnc #Hematology ... #PlasmaCell #Hypercalcemia ... #Anemia #Clinical
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... mmol/L - Consider cause ... clinical scenario, ECG ... Gluconate IV Shift ... Prevention - Consider cause
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperphosphatemia • Hyperkalemia ... Hypocalcemia Hypercalcemia ... Constipation • Nausea ... Hyponatremia • Nausea
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... • Secondary (e.g ... #Normocytic #Anemia ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Poisoning • Anemia ... Chronic Disease (e.g ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Liver Failure • Hypercalcemia ... Neoplastic / Hematologic ... • Anemia • ... • Drug Abuse (e.g
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Causes: Chronic ... TlBC > 18% • Anemia ... #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Gammopathies C - HyperCalcemia ... 40 ml/min A - Anemia ... Causes of false- ... MGUS #diagnosis #hematology ... #oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia