13 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Intracellular Shift ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... Suspicion for Hyperkalemia ... Intracellular Shift ... potassium #high #nephrology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Lower risk of hypercalcemia ... edgarvlermamd - Nephrology ... Binders #Table #Comparison ... #Pharmacology # ... Nephrology
Adult Vancomycin Guidelines
The information below provides general dosing guidelines for vancomycin. A maintenance regimen of 15-20
provides general dosing ... regimen of 15-20 mg/kg ... is the accepted dosing ... reference source and nephrology ... #Management #Pharmacology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
restricted due to hypercalcemia ... Only* #CKD #Nephrology ... Hyperphosphatemia #Dose #Dosing ... #Pharmacology #
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
with caution - e.g ... #pharmacology #comparison ... #medications #dosing
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Transcellular Shift ... • Cell Lysis (e.g ... IntercellularShift #Nephrology