29 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Medications Renal ... Losses Non-renal ... Diagnosis #Algorithm #nephrology
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Sites #Action #Nephron ... #Pharmacology # ... Nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
action on the nephron ... Loop diuretic (e.g ... triamterene) #nephron ... #diuretics #pharmacology ... #nephrology #medications
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
distal component of Nephron ... hyporenin hypoaldo, hyperkalemic ... absorption in distal nephron ... and decreased renal ... KidneyDisease #nephrology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron ... Sites #Action #nephrology ... #pharmacology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... (if preserved renal ... LouLectures #Hyperkalemia ... management #potassium #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Intracellular Shift ... Renal artery stenosis ... NephTwitter) #Hypokalemia ... Causes #Workup #Nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... - Shift from extracellular ... pump inhibitor - Renal ... differential #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Intracellular Shift ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal ... potassium #high #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
oxoproline) • Renal ... Renal acidosis ... Hypokalemia ... Generalized distal nephron ... diagnosis #causes #nephrology