51 results
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... higher risk of hyperkalemia ... Pgp-dependent drugs (e.g ... contraindications #table ... #bloodpressure
Useful Intravenous Antihypertensive Agents
- Nicardipine
- Clevidipine
- Labetalol
- Esmolol
- Nitroglycerin

Dr. Josh Farkas https://twitter.com/PulmCrit

#Antihypertensive #Agents #Hypertensive #Emergency #Pharmacology
Hypertensive #Emergency #Pharmacology ... #Table #Intravenous ... #CriticalCare #BloodPressure
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... clinical scenario, ECG ... Gluconate IV Shift ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia
Oral anti-hypertensives with relative fast onset of action (Hypertensive Emergency)

The key concern with oral antihypertensive agents
up-titrating medications (e.g ... Emergency #Management #Pharmacology ... #Table #BloodPressure
Intern Pocket Cards - Inpatient Blood Pressure Management Guide
ß-blockers:
 • Metoprolol, Carvedilol, Labetalol
 • Bradycardia, heart
Valsartan • AKI, hyperkalemia ... #hypertension #BloodPressure ... medications #Inpatient #pharmacology ... #table #agents
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
- Medications (e.g ... cisplatin) - Chronic hypercalcemia ... - Chronic hypokalemia ... renal diseases (e.g ... Differential #Diagnosis #Table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... #medications #pharmacology ... #table #comparison
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table