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diagnosis management nephrology treatment differential binding blood hematology lr ns product reactions rhabdomyolysis agents aldosterone angiotensin cardiology classification crystalloids digoxin
Key Characteristics of Old and New Potassium-Binding Agents - Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd #Potassium #Binding #KBinders #Kayexelate
edgarvlermamd #Potassium ... #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium Binders for Management of Hyperkalemia • SPS - Sodium polystyrene sulfonate • Patiromer (veltassa) •
Potassium Binders ... Management of Hyperkalemia ... #Hyperkalemia # ... treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... #Binding #Hyperkalemia ... #medications #pharmacology ... #table #comparison
Characteristics of Commonly Used Phosphate Binders Aluminum - Potent and effective - Useful for
Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... requirements - Lack of hypercalcemia ... range - Lack of hypercalcemia ... #Table #Comparison
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte - Causes hyperkalemia? - Safe to
hyperkalemia? ... patients with hyperkalemia ... Update: AKI in NS row ... #Crystalloids #pharmacology ... #indications #comparison
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
• LDH ↑ • Hyperkalemia ... /Late - Hypercalcemia ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... Because digoxin binds ... (or low potassium
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
Saline (NS) - Comparison ... 130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... #pharmacology #
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
aldosterone which does a lot ... sodium, which causes ... inhibiting drug classes ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Shift of extracellular ... Monitor potassium ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes
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