69 results
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
fludrocortisone step 3 = diuretic ... determine response to diuretic ... #kaliuresis #management ... criticalcare #treatment #diuretics ... #diuresis #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Transcellular Shifts ... thiazide-like diuretics ... Postobstructive diuresis ... , Osmotic diuresis ... use), Gitelman's
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Loop and thiazide diuretics ... - Hypokalemia ... - Osmotic diuresis ... Post-obstructive diuresis ... syndromes - Gitelman
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Transcellular shifts ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... #Nephrology #Pharmacology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... Hypomagnesemia • Osmotic diuresis ... tubular acidosis • Gitelman's ... Transcellular shift ... amzn.to/2LmUODZ #Hypokalemia
Hypophosphatemia - Differential Diagnosis Algorithm

Transcellular Shift
 • Recovery From DKA
 • Refeeding Syndrome
 • Acute Respiratory
Transcellular Shift ... Alkalosis • Hypokalemia ... Syndrome • Osmotic Diuresis ... Acetazolamide and Thiazide Diuretics
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... Start with LOOP DIURETICS ... , address diuretic ... Early nephrologv ... Fluid #Balance #management
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... function) - Loop diuretic ... #management #potassium ... #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
- Shift from extracellular ... foscarnet - Diuretics ... and other loop diuretics ... antiretroviral therapy - Diuretics ... differential #diagnosis #nephrology