13 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
nonspecifically binds ... patients sensitive to high ... #medications #pharmacology ... #table #comparison ... #binders
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
• Consider K+ binder ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... disturbances, shift ... , changes on ECG ... , and Table 3 summarizes ... medications used
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
with caution - e.g ... #pharmacology #comparison ... #treatment #medications ... dosing #drugs #table
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... Non calcium phos binders ... Syndrome #TLS #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Shift of extracellular ... fluid/Lactated ringers ... per day until stable ... #Differential #Diagnosis
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... #pharmacology #
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... #Diagnosis #Management
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... #Medications #Table