30 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... #differential # ... pathophysiology #pharmacology
Benign Adrenal Mass - Differential Diagnosis Algorithm
Hyperplasia - Often Bilateral
 • Congenital Adrenal Hyperplasia
 • ACTH
Adrenal Mass - Differential ... Aldosterone Excess - Hypertension ... +/- Hypokalemia ... Pheochromocytoma (Paroxysmal Hypertension ... AdrenalMass #Benign #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Intracellular Shift ... #differential # ... causes #potassium #high
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm Hypertensive ... : • High Al, Low ... Gitelman's syndrome #Hypokalemia ... #Differential #
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Intracellular Shift ... #differential # ... causes #potassium #high
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... patients sensitive to high ... #medications #pharmacology ... #table #comparison
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... - Shift from extracellular ... - Insulin (high ... #Medications #differential
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Insufficiency Differential ... abdominal pain, hypotension ... hyponatremia, hyperkalemia ... insufficiency likely: • High ... Insufficiency #Differential
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
- Workup and Differential ... with previously stable ... disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... Workup #causes #Differential
Malignant Adrenal Mass - Differential Diagnosis Algorithm
Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Adrenal Mass - Differential ... Aldosterone Excess Hypertension ... +/- Hypokalemia ... Pheochromocytoma (Paroxysmal Hypertension ... AdrenalMass #Malignant #Differential