44 results
management diagnosis medications table differential causes nephrology comparison high algorithm idsa pharmacotherapy cardiology hivaids hypokalemia infections opportunistic pathophysiology prevention tuberculosis
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... LouLectures #Hyperkalemia
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
INDICATION: Treatment ... oral suspension DOSING ... from other oral drugs ... this from other drugs ... #Pharmacology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... and calcium • Dosing ... of aspiration #Potassium ... #medications #pharmacology
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... reactions Common Drugs ... • Recent IV potassium ... Intracellular Shift ... diagnosis #causes #potassium
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... shift - Acidosis ... drugs - Transfusion ... Renal failure* - Drugs—potassium-sparing ... anti-inflammatory drugs
REBEL Review 71: Treatment of Thyroid Storm Propranolol Esmolol Propylthiouracil (PTU) Methimazole Saturated Solution of Potassium
REBEL Review 71: Treatment ... Saturated Solution of Potassium ... table #management #treatment ... #pharmacology # ... comparison #Dosages #dosing
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... reactions Common Drugs ... • Recent IV potassium ... Intracellular Shift ... diagnosis #causes #potassium
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Reconsider treatment ... and parenteral potassium ... Intracellular K+ Shift ... Management #Algorithm #treatment ... #potassium #high
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