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diagnosis management differential nephrology causes potassium hypokalemia algorithm neurology tls classification hematology lysis medications rhabdomyolysis rheumatology signs symptoms tumor tumorlysis
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... #Hypokalemia ... potassium #low #pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Allantoin (High ... Hypocalcemia • Hyperkalemia ... #TLS #Pathophysiology
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... ) occur in high ... malignancies Treatments ... #Tumor #Lysis #Syndrome ... #TLS #oncology
BRASH Syndrome B - Bradycardia R - Renal failure A - AV nodal blockade S - Shock H - Hyperkalemia Typical ECG
BRASH Syndrome ... ) BRASH Treatment ... • Aggressive treatment ... DrEricStrong #BRASH #Syndrome ... diagnosis #management #pathophysiology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... mmol creatinine) High ... Low-normal EABV, High ... #hypokalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... Intracellular Shift ... - Tumor lysis syndrome ... causes #potassium #high
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome ... diagnosis #management #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... : • Pathophysiology ... Spontaneous if high ... hydration - Hyperkalemia
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... - Shift from extracellular ... - Insulin (high ... renal Fanconi syndrome
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... blocks, QRS axis shift ... , asystole #hyperkalemia ... #potassium #high ... management #algorithm #treatment
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