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diagnosis hyperkalemia differential treatment high algorithm nephrology criticalcare foamed hematology pathophysiology product reactions rhabdomyolysis table aldosterone anesthesia anesthesiology angiotensin cardiac
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... peaks 1-2h) • Blood ... LouLectures #Hyperkalemia ... #management #potassium
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... Benyzlpenicillin, blood ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... Intracellular Shift ... Blood transfusion ... differential #diagnosis #causes ... #potassium #high
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
sodium, which causes ... increased blood ... This decreases blood ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Crush injury • Blood ... Intracellular Shift ... Blood transfusion ... differential #diagnosis #causes ... #potassium #high
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
Hyperkalemia Management ... • Treat the cause ... and parenteral potassium ... Intracellular K+ Shift ... #treatment #potassium
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Emergency Management ... of Hyperkalemia ... mmol/L - Consider cause ... Gluconate IV Shift ... Monitor K+ and Blood
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... - Hyperkalemia ( ... , in states of hypokalemia ... Pathophysiology #cardiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Summary Causes ... UA positive for blood ... Shift of extracellular ... Monitor potassium
Causes of Hyperkalemia Pseudohyperkalemia - Tourniquet use - Hemolysis (in vitro) - Leukocytosis - Thrombocytosis Intra- to extracellular
Causes of Hyperkalemia ... shift - Acidosis ... Transfusion of aged blood ... acidosis) #Hyperkalemia ... #Causes #diagnosis
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