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diagnosis management differential hyperkalemia treatment anesthesia anesthesiology criticalcare intraoperative pathophysiology workup algorithm blood bradycardia cardiac chf classification clinical comparison complexes
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... pathophysiology #pharmacology ... #potassium #medications
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... intracellular calcium causes ... high potassium levels ... (or low potassium ... Pathophysiology #cardiology
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
Have a high index ... CM5 continuous ECG ... abnormalities particularly potassium ... consultation with cardiology ... Intraoperative #Checklist
Hyperkalemia Management Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... site/line where potassium ... minutes-hour) -Shift ... or dialysis • SLOW ... #high
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... NS #comparison #pharmacology
The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
we introduce a high ... causes Hyperkalemia ... The high CL- content ... #foamed #criticalcare ... diagnosis #treatment #pharmacology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
heart disease Causes ... Hypomagnesemia • Hypokalemia ... classified as: • Low ... percent PVCs/day • High ... #differential #cardiology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
mental status and low ... ECG is vital while ... patient causing hypovolemia ... the determined cause ... treatment #table #foamed
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
Check fresh gas flow ... (eg. remifentanil ... Also consider: high ... Intraoperative #Checklist ... Management #Workup #Cardiology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... extracellular shift ... Drug-associated: heparin, low-molecular-weight ... Differential #Diagnosis #High ... #Potassium #Classification
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