22 results
diagnosis differential hyperkalemia algorithm management treatment pharmacology checklist comparison low pathophysiology anesthesia anesthesiology binders binding cardiac criticalcare crystalloids cva digoxin
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... vomiting) • Low K ... Diagnosis #Algorithm #nephrology ... #low #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... #urine #potassium ... algorithm #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Intracellular Shift ... Medications 2. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... shift of K (Succinylcholine ... #pharmacology #potassium ... #medications #druginduced
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... urinary losses: • High ... #nephrology #low
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
• Treat the cause ... and parenteral potassium ... Intracellular K+ ... Shift 3) K+ Excretion ... #high
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... depletion • Consider K+ ... and ECG changes ... blocks, QRS axis shift ... #potassium #high
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... intracellular calcium causes ... - Hyperkalemia ( ... high potassium levels ... Pathophysiology #cardiology
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