27 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... 8.0 mg/dL • Potassium ... Treatment of TLS ... #TumorLysis #Syndrome
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... • Refeeding syndrome ... Thyrotoxicosis Medications ... Transcellular shifts ... nephrology #low #potassium
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... is caused by excess ... potassium intake ... transcellular shifts ... renal function, medication
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Renal loss • Medication ... • Gitelman's syndrome ... • Bartter's syndrome ... Transcellular shift ... Diagnosis #Algorithm #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... #Hypokalemia ... #potassium #low
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... the Treatment of ... disturbances, shift ... Table 3 summarizes medications ... #Management #Medications
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... constipation, diarrhea, nausea ... ); nausea, vomiting ... of aspiration #Potassium ... #medications #pharmacology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... HIV, Influenza, TSS ... Shift of extracellular ... Monitor potassium ... Diagnosis #Management #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Intracellular Shift ... - Tumor lysis syndrome ... Medications 2. ... differential #diagnosis #causes ... #potassium #high