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diagnosis differential nephrology management causes hyperkalemia tls algorithm oncology high hyperphosphatemia rhabdomyolysis acutekidneyinjury adrenal cairoandbishop classification emergencies endocrinology etiology framework
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... 8.0 mg/dL • Potassium ... #TumorLysis #Syndrome
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Initial workup ... ≥ 8 mg/dL • Potassium ... of the above Treatment ... #Lysis #Syndrome
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... hyperphosphatemia, #hypocalcemia ... Presentation #TLS #Workup
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Algorithm Before evaluating ... treated with IV potassium ... Renin secreting tumor ... #differential #potassium
Adrenal Incidentalomas: Hormone Evaluation • Zona Glomerulosa: Primary Hyperaldosteronism? - Aldosterone and renin
Aldosterone and renin if hypokalemia ... Fasciculata: Cushing Syndrome ... for those with tumor ... mendesthiagob #Adrenal #Tumors ... #Diagnosis #workup
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... Renin secreting tumor ... #urine #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Recent IV potassium ... Intracellular Shift ... release due to cell lysis ... Transfusion reaction - Tumor ... lysis syndrome
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... Rhabdomyolysis, Tumor ... lysis syndrome, ... Transcellular Shift ... Diagnosis #Framework #Workup
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• Recent IV potassium ... Intracellular Shift ... release due to cell lysis ... Transfusion reaction - Tumor ... lysis syndrome
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... organ damage • Treatment ... Lysis Syndrome: ... hydration - Hyperkalemia ... #Lysis #Syndrome
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