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neurology differential causes management cauda caudaequina compylobacterjejuni equina flaccidpalsy gbs guillainbarresyndrome landrysyndrome manifestations neuromuscular neuromyelitis nmo optica rheumatology signs sjogrens
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Syringomyelia, Tetanus, Transverse ... Myelitis, Trauma ... #differential #diagnosis ... #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
disturbances, facial ... Many others • Transverse ... myelitis: Motor ... pain • Extra-CNS ... Manifestations #diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... that results in CNS ... Myelitis Diagnosis ... brain and/or optic nerve ... #Myelitis #diagnosis
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
Guillain–Barré syndrome ... Differential diagnosis ... Multiple Sclerosis: CNS ... prominent cranial nerve ...  Transverse myelitis
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
compression of nerve ... Differential Diagnosis ... myelopathy • Transverse ... myelitis • Multiple ... #causes #neurology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
lacrimal glands: • Focal ... myelopathy, cranial nerve ... peripheral neuropathy, transverse ... myelitis • 8%- ... phenomenon (16%) MSK
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