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diagnosis causes treatment nephrology rhabdomyolysis abscess anemia cbc comparison curve dissociation druginduced effects gitelman hematology hospitalization hyperkalemia hypokalemia lactated left
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... Benyzlpenicillin, blood ... #hyperkalemia #differential ... #pharmacology # ... potassium #medications
Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
Curve Left Shift ... • stored red blood ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Differential #
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Left Shift: • ... Metamyelocyte (Left Shift ... #differential # ... CBC #hematology #pathophysiology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... Can give with blood ... - Citrate in blood ... transcellular shift ... NS #comparison #pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... UA positive for blood ... Shift of extracellular ... Monitor potassium
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... drop in your pts blood ... These shifts of ... Hospitalization #causes #pathophysiology ... #differential #
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Leukocytosis, anemia ... • Sputum/Blood ... Lung Abscess Differential ... Abscess #pulmonary #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Normal or low blood ... ratio 0.5%) Differential ... Supplement: • Potassium ... diagnosis #nephrology #management ... #pathophysiology
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