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diagnosis hyperkalemia nephrology hematology product reactions rhabdomyolysis treatment algorithm cardiology comparison digoxin druginduced edema effects lactated lr medications ncpe noncardiogenic
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... Benyzlpenicillin, blood ... #hyperkalemia #differential ... #pharmacology # ... potassium #medications
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Alwavs Repeat Blood ... Diagnosis #Algorithm #causes ... #potassium #high ... #pathophysiology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... Intracellular Shift ... #diagnosis #causes ... #potassium #high
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
130 mEq/L • Potassium ... transcellular shift ... • Saline Causes ... densa receives high ... NS #comparison #pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... Intracellular Shift ... #diagnosis #causes ... #potassium #high
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... intracellular calcium causes ... Hyperkalemia (high ... Because digoxin binds
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium ... #Summary #causes
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
Edema (NCPE) - Differential ... Diagnosis Framework High ... • High-altitude ... : The shift of fluid ... #differential #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Summary Causes ... UA positive for blood ... Shift of extracellular ... Monitor potassium
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... - Differential ... Framework • Cellular Shift ... hyperkalemia: Blood ... #potassium #high
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