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differential causes nephrology treatment rhabdomyolysis agents algorithm anesthesia anesthesiology antifungal cardiology checklist classification coccidioides coccidioidomycosis diuresis diuretics druginduced excretion hypokalemia
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... reactions Common Drugs ... Intracellular Shift ... Medications 2.
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... reactions Common Drugs ... Intracellular Shift ... Medications 2.
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... - Shift from extracellular ... - Insulin (high ... #Medications #differential ... #diagnosis #nephrology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
- Differential Diagnosis ... Framework • Cellular Shift ... hyperosmolality - Medications ... #Causes #potassium ... #high
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... STOP offending medications ... #Diagnosis #Management ... #Treatment #potassium
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
and Management ... Drugs (Statins), ... Shift of extracellular ... Monitor potassium ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Framework and Management ... - Toxins - Drugs ... Shift of extracellular ... Monitor potassium
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
Consider known drug ... Also consider: high ... myocardial infarction, hyperkalaemia ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
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