33 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Clenching of fist during ... phlebotomy High ... Intracellular Shift ... Medications 2.
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Dialysis Serum potassium ... blocks, QRS axis shift ... #hyperkalemia #potassium ... #high #diagnosis ... management #algorithm #treatment
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Clenching of fist during ... phlebotomy High ... Intracellular Shift ... Medications 2.
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #Hyperkalemia #medications ... #pharmacology #
Pearls for Treatment of Alcohol Use Disorder

First-line pharmacotherapies for moderate to severe AUD include naltrexone and
Pearls for Treatment ... or at high risk ... UseDisorder #Management #Treatment ... Screening #Addiction #Medications ... #Pharmacology
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
Dermatitis - Topical Treatment ... Corticosteroids - High ... If patients using ... Dermatitis #Topical #Treatment ... #Medications #Pharmacology
A quick infographic describing some of the common reversal agents used by anesthesiologists, their mechanism of
mechanism of action, dosing ... anesthesiology #treatment ... #medications ... anaesthesia and critical ... Pharmacology of
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Eosinophils < 100 Dosing ... recommendations for the treatment ... the use of this medication ... won’t have any clinical ... #Pharmacology #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Dermatomyositis Clinical ... Shift of extracellular ... Monitor potassium ... #Differential #Diagnosis