31 results
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Transcellular Shift ... K-ATPase which imports ... Beta-Agonist - Refeeding ... Syndrome #Hypokalemia ... potassium #low #pathophysiology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... Electrolyte/fluid shifts ... • These shifts ... abnormalities before refeeding ... Differential #Diagnosis #Pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Syndrome: - Little ... Metabolic Acidosis • Shift ... #Syndrome #diagnosis ... #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... paralysis • Refeeding ... syndrome • Thyrotoxicosis ... Transcellular shifts
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Redistribution/ Shift ... with depletion: Refeeding ... ), Hungry bone syndrome
Hypophosphatemia - Differential Diagnosis Algorithm

Transcellular Shift
 • Recovery From DKA
 • Refeeding Syndrome
 • Acute Respiratory
Transcellular Shift ... Recovery From DKA • Refeeding ... Syndrome • Acute ... Osteomalacia • Fanconi Syndrome
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... Prevention of variceal rebleeding ... hepatology #management #pharmacology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Transcellular Shift ... : Refeeding Syndrome ... Tumor Genesis Syndrome ... FGF23: Fanconi Syndrome
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Transcellular Shift ... : Refeeding, Glycolysis ... alkalosis, Hungry bone syndrome ... Tumor genesis syndrome ... FGF-23: Fanconi syndrome
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #