39 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Algorithm Symptoms ... of associated autoimmune ... disease (e.g. dryness ... disease, Persistent ... #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential Diagnosis ... Other: NAFLD, Autoimmune ... Causes #Acute #algorithm ... #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... Hepatitis - Autoimmune ... hepatitis - Wilson disease ... #Differential #Hepatology ... #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... • Autoimmune: ... extrahepatic source - Tests ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
→ liver test abnormalities ... Hemochromatosis, Wilson's disease ... Other: NAFLD, Autoimmune ... HELLP, Celiac disease ... #hepatology #algorithm
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
female-predominant disease ... disease, First-degree ... cell mediated autoimmune ... T-cell mediated BEC injury ... Pathophysiology #hepatology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... Cold agglutinin disease ... #antiglobulin #test ... #Hemolysis #hematology ... #diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... - PSC - Other ... #Differential #Diagnosis ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Algorithm Severe ... • Ischemia • Autoimmune ... • Cholestatic disease ... Bile Ducts • PSC ... Others #LFTs #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Liver Function Tests ... - Differential Diagnosis ... Algorithm for Transaminitis ... Transaminitis #Algorithm ... #diagnosis #hepatology