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differential hepatology causes hepatitis transaminitis abnormal acidosis acute classification dili elevated elevatedmcv elevation gastroenterology hemolysis hepatocellular idiosyncratic induced lactate lactic
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... → liver test abnormalities ... valproate, azoles), Drugs ... #Diagnosis #hepatology ... #LFTs #hepatitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... gastroenterology #algorithm
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... , Recreational Drugs ... #Acute #algorithm ... #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... Blood Smear • Drugs ... • Liver Disease ... #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... • Cholestatic disease ... Bile Ducts • PSC ... • Others #LFTs
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
, PCH, Evans Syndrome ... , Liver Disease, ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... extrahepatic source - Tests ... #algorithm #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... or renal injury ... tests before beginning ... 30mmHg) - Severe anemia ... Injury: • Reduced
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