19 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Algorithm #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... Transaminase >> Alkaline ... #FunctionTest #LFTs ... #diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
test abnormalities ... compared with alkaline ... HELLP, Celiac disease ... #hepatology #algorithm ... Transaminitis #LFTs
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... magnitude of enzyme elevation ... disease; T2DM, ... #LFTs #Abnormal ... #Algorithm #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... #Elevated #Abnormal ... #diagnosis #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT ... hepatocyte - Elevation ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis ... #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... Bile Ducts • PSC ... • Others #LFTs ... #Hepatology #LiverEnzymes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... specificity to elevated ... extrahepatic source - Tests ... #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... Labs: • Alkaline ... normal or slightly elevated ... or higher • Liver ... #workup #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Algorithm Symptoms ... of autoimmune disease ... Elevated ALP 2. ... Liver biopsy findings ... #Algorithm #hepatology