18 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
) Three syndromes ... Elevated Liver tests ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... quadrant discomfort Signs ... of autoimmune disease ... Elevated ALP 2. ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... and hepatorenal syndrome ... • Budd Chiari syndrome ... Veno-occlusive disease ... #causes #hepatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Elevated Liver tests ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... extrahepatic source - Tests ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... cholestasis → Cirrhosis ... failure PBC Signs ... obstruction • ALP ... #workup #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... ALP, alkaline phosphatase ... alcohol-related liver disease ... non-alcoholic fatty liver disease
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... of Pregnancy (AFLP ... obstetrics #hepatitis #comparison ... #differential #diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... Alcoholic liver disease ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... liver #chemistry #diagnosis
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
dullness, puddle sign ... incisional). 3) Signs ... of underlying disease ... 3) Optional tests ... #hepatology