26 results
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
of germinative skin ... Basophils/Histamine 4) Skin-homing ... #Dermatology #Rash ... Nikolsky #Algorithm #Differential ... #Ddxof
Fluid-filled Rash - Diagnostic Algorithm.  Pustule: 1) Pustules more commonly suggest an infectious process (bacterial,
Fluid-filled Rash ... proteins in the skin ... #Dermatology #Rash ... Bullous #Algorithm #Differential ... #Ddxof
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
New-onset fever with rash ... sulfa-drug - Skin ... #Dermatology #Rash ... Targetoid #Algorithm #Differential ... #Ddxof
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... parallel to lines of skin ... palms/soles - Differential ... ChristmasTree #Rash ... Pityriasis #rosea #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... vasculitis Skin ... also occur Skin ... 16%) • Painful skin ... and gangrene Skin
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... Disease #diagnosis #management
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Skin involvement ... Resolution > 15 days Differentials ... Exanthematous Pustulosis Management
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... biopsy preferred Differential ... Sporotrichiosis #Infection #clinical
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin