51 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Hyperpigmentation Differentials ... the Mnemonic "no skin ... #5 #diagnosis #differential ... #symptoms #signs ... #dermatology #skin
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Symptoms: Tiredness ... , Dry coarse skin ... Goitre), Dry skin ... #PhysicalExam #Endocrinology
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Acute onset of skin ... >2 of: • skin ... Signs / Symptoms ... #Anaphylaxis #pathophysiology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome - Signs ... and Symptoms Generalized ... Muscular: Weakness Skin ... #Symptoms #diagnosis ... #endocrinology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Ill-appearing, vital sign ... sulfa-drug - Skin ... Color #Targetoid #Algorithm ... #Differential #
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic Algorithm ... Pathophysiology: ... of germinative skin ... Basophils/Histamine 4) Skin-homing ... #Differential #
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Femoral Cutaneous Nerve ... purely sensory nerve ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
Menorrhagia - Skin ... • Skin is ... amenorrhea - Skin ... • Warm, moist skin ... #endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... diabetes Key signs ... /symptoms of HHS ... hypovolemia (dry MM, skin