43 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #rashes #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
erythematosus (SLE ... ) Signs / Symptoms ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Ill-appearing, vital sign ... New-onset fever with rash ... sulfa-drug - Skin ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Femoral Cutaneous Nerve ... intervertebral disc disease ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... • Polymorphous rash ... - Generalized Skin ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... , the differential ... includes Kawasaki disease ... erythematous rash
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... ) Differential Diagnosis ... #signs #symptoms