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Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
thrombophlebitis Skin ... • Shin splints ... Brittle nails - Skin ... skin • Inflammation ... pain/swelling - Fever
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... syndrome (SSS) ... , the differential ... #Differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
) is a skin condition ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... • Rheumatic fever ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... on texture of skin ... Suggestive of: Rheum Fever ... migrans: • Target sign ... dermatology #arthritis #skin
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
Scarlet fever • ... Delayed-type skin ... folds #Scarlet #fever ... diagnosis #clinical #photo ... #signs #symptoms
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Secondary: • Fever ... , malaise • Rash ... testing • No symptoms ... lesions in bone, skin ... #signs #diagnosis
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
& hemorrhagic rash ... ; symptoms of shock ... that persists as skin ... Vesicular & pruritic rash ... non-specific viral symptoms
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
SKIN RASHES ... Skin rashes ... the presence of fever ... and systemic signs ... petechiae; #purpura; #rash