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Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... • Shin splints ... Brittle nails - Skin ... skin • Inflammation
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... syndrome (SSS) ... , the differential ... #Differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... ) is a skin condition ... inflamed or blistered skin ... development of skin ... deeper into the skin
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... • Rheumatic fever ... Scleroderma Thickened skin ... arthritis Discoid skin ... #skin #rashes #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Causes of Acute ... Onset Fever - Differential ... Meningitis • Skin ... Neuroleptic malignant syndrome ... #Fever #Acute
Symptoms and signs of Leptospirosis
Acute phase:
 - Fever and headache
 - Conjunctival suffusion, jaundice, and photophobia
Symptoms and signs ... Leptospirosis Acute ... phase: - Fever ... - Abdominal pain ... - Skin rash (
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Medical History: • Skin ... localizing signs ... leptospirosis • Skin ... Rickettsioses, bacterial skin ... , Lassa fever, acute
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... Red Flags: • Fever ... • Skin changes ... • Urinary symptoms ... Abdominal cutaneous nerve
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
Mediterranean Fever ... by serositis • Acute ... Abdominal cutaneous nerve ... Positive Carnett's sign ... #differential #