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Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... • Shin splints ... Brittle nails - Skin ... skin • Inflammation
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... • Rheumatic fever ... Scleroderma Thickened skin ... arthritis Discoid skin ... #skin #rashes #
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... syndrome (SSS) ... includes Kawasaki disease ... #Differential
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... ) is a skin condition ... inflamed or blistered skin ... development of skin ... deeper into the skin
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Sjögrens (15%) Skin ... lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs
Symptoms and signs of Leptospirosis
Acute phase:
 - Fever and headache
 - Conjunctival suffusion, jaundice, and photophobia
Symptoms and signs ... Leptospirosis Acute ... phase: - Fever ... - Abdominal pain ... - Skin rash (
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses
Medical History:
 • Skin exposure to
Medical History: • Skin ... localizing signs ... leptospirosis • Skin ... Rickettsioses, bacterial skin ... , Lassa fever, acute
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... Red Flags: • Fever ... • Skin changes ... • Urinary symptoms ... Abdominal cutaneous nerve
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Onset Fever - Differential ... Meningitis • Skin ... Neuroleptic malignant syndrome ... • Sickle Cell disease ... #Fever #Acute
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin