42 results
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... eosinophilia Primary ... Autoimmune thyroid disease ... : - Pale skin ... Insufficiency #Signs
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Skin Lesions == ... • Xerosis (dry skin ... Skin Lesion / Systemic ... Cholestatic liver disease ... BUN: • Chronic renal
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
progressive fibrosis of skin ... LcSSc) - distal skin ... DcSSc; diffuse) - skin ... Hepatic: PBC (primary ... changes): skin
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Primary Adrenal ... Insufficiency Addison's Disease ... Infiltrative Disorders ... autoimmune endocrine disorder ... patches on the skin
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... of hair, eyes, skin ... sclerosis (white "ash ... • Addison's disease ... #skin #dermatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders ... - Differential Diagnosis ... arthritis - with the skin ... like “butterfly rash ... #msk #Differential
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... , the differential ... includes Kawasaki disease ... erythematous rash
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Infection #clinical #photo
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve ... disease (30%): ... erythematosus #signs
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #diagnosis #management